Dengue epidemic in the State of Rio Grande do Norte, Brazil, in 1997
- 1 May 1999
- journal article
- Published by Oxford University Press (OUP) in Transactions of the Royal Society of Tropical Medicine and Hygiene
- Vol. 93 (3) , 247-249
- https://doi.org/10.1016/s0035-9203(99)90008-1
Abstract
During 1997 a large dengue epidemic occurred in Rio Grande do Norte, a State in north-east Brazil. The cocirculation of dengue virus type 1 and dengue virus type 2 was demonstrated by virus isolation in Aedes albopictus clone C6/36 cell-line and by reverse transcriptase-polymerase chain reaction (RT-PCR). IgM capture enzyme-linked immunosorbent assay confirmed 52·3% of the 8105 studied cases and dengue antigen was demonstrated by immunohistochemical reaction on hepatocytes from 2 out of 5 fatal cases studied. Individual risk factors for development of dengue haemorrhagic fever/dengue shock syndrome, such as hypertension, diabetes mellitus and bronchial asthma, are discussed.Keywords
This publication has 13 references indexed in Scilit:
- Origins of Dengue Type 2 Viruses Associated with Increased Pathogenicity in the AmericasVirology, 1997
- Dengue epidemic in the state of Rio de Janeiro, Brazil, 1990–1: co-circulation of dengue 1 and dengue 2 serotypesEpidemiology and Infection, 1993
- Levels of IgM antibodies against dengue virus in Rio de Janeiro, BrazilResearch in Virology, 1992
- Why dengue haemorrhagic fever in Cuba? I. Individual risk factors for dengue haemorrhagic fever/dengue shock syndrome (DHF/DSS)Transactions of the Royal Society of Tropical Medicine and Hygiene, 1987
- Mosquito Cell Cultures and Specific Monoclonal Antibodies in Surveillance for Dengue VirusesThe American Journal of Tropical Medicine and Hygiene, 1984
- Dengue Haemorrhagic Fever in Cuba. II. Clinical investigationsTransactions of the Royal Society of Tropical Medicine and Hygiene, 1984
- Dengue Virus-Specific and Flavivirus Group Determinants Identified with Monoclonal Antibodies by Indirect ImmunofluorescenceThe American Journal of Tropical Medicine and Hygiene, 1982
- Epidemic Dengue 3 in Central Java, Associated with Low Viremia in Man *The American Journal of Tropical Medicine and Hygiene, 1981
- Isolation of a Singh's Aedes albopictus Cell Clone Sensitive to Dengue and Chikungunya VirusesJournal of General Virology, 1978
- Techniques for Hemagglutination and Hemagglutination-Inhibition with Arthropod-Borne VirusesThe American Journal of Tropical Medicine and Hygiene, 1958