Optical image reconstruction with deconvolution in light diffusing media

Abstract
We describe a simple reconstruction method for diffuse optical imaging based on modified back-projection approach for medical tomography. These modifications are based primarily on the deconvolution of the broadened image by a point spread function which is dependent on the scattering of light in tissue. The nonlinearities in the image formation are handled empirically by coordinate transformations. Although our method is an approximate image reconstruction technique, it may provide a basis for rapid, real time medical monitoring by using optical projections. We have applied this method to experimental projections taken by parallel and fan beam tomography geometries on biomedical phantoms with multiple objects. The results presented in this report indicate considerable improvement in image resolution.