Transplantable Metastasizing Prostate Adenocarcinomas in Rats2

1 March 1975

journal article
research article
Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute

Vol. 54 (3) , 643-649
https://doi.org/10.1093/jnci/54.3.643

Abstract

Three spontaneous prostate adenocarcinomas from aged, randombred, germfree Lobund Wistar rats were transplanted, without change, through several series of conventional Lobund Wistar rats. One tumor type differed histologically from the other two tumor types. Rats with subcutaneously transplanted tumors developed metastatic tumors in the lymph nodes and lungs. No microbial agent was detected in the tumor cells.

Keywords

NEOPLASMS
RATS
PROSTATE CANCER
WISTAR
LYMPH NODES
LUNG
NEOPLASM METASTASIS
TUMOR CELLS