Kinetic Studies of Fast Equilibrium by Means of High-Performance Liquid Chromatography. XIII. Separation of Rotamers of N-Alkyl-Substituted Amides

Abstract
Rotamers of N-alkyl-substituted amides have been separated by means of high-performance liquid chromatography(HPLC) at low column temperatures. The ratios of the E-rotamers have been found to increase in the following order: propionamides<acetamides<formamides.