Enantioselective Metal-catalyzed Baeyer-Villiger Oxidation of Cyclobutanones
- 1 October 1997
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1997 (10) , 1151-1152
- https://doi.org/10.1055/s-1997-977
Abstract
Optically active lactones are obtained by metal-catalyzed aerobic oxidation of prochiral cyclobutanones. Starting from 3-monosubstituted substrates lactones with moderate enantioselective (up to 47% ee) have been obtained. Kelly's tricyclic ketone 8 provides the corresponding lactone with 91% enantiomeric excess.Keywords
This publication has 0 references indexed in Scilit: