One Hundred Percent Tumor Induction in Mouse Skin after Repeated β Irradiation in a Limited Dose Range
- 1 September 1988
- journal article
- research article
- Published by JSTOR in Radiation Research
- Vol. 115 (3) , 488-494
- https://doi.org/10.2307/3577298
Abstract
Repeated .beta. irradiation of the backs of mice three times a week with radiation doses of 250 to 1180 cGy per exposure induced 100% incidence of tumors. The incidence of skin tumors appeared to be determined by the total number of repeated exposures in this dose range. An abrupt delay in tumor emergence was observed when the radiation dose was reduced from 250 to 150 cGy per exposure, indicating the existence of a critical threshold. Mouse skin resembles human skin rather than rat skin in its response to radiation.This publication has 4 references indexed in Scilit:
- Evidence for Repair of Premutational Damage from Split X-Ray DosesRadiation Research, 1980
- The effect of dose fractionation on γ-radiation induced mutations in mammalian cellsMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1977
- Dose Rate: Its Effect on the Survival of HeLa Cells Irradiated with Gamma RaysRadiation Research, 1964
- Tumours of the Skin and other Delayed Effects of External Beta Irradiation of Mice Using 90Sr and 32PBritish Journal of Cancer, 1962