A two‐step one‐pot radiosynthesis of the potent dopamine D2/D3 agonist PET radioligand [11C]MNPA
- 23 January 2009
- journal article
- Published by Wiley in Journal of Labelled Compounds and Radiopharmaceuticals
- Vol. 52 (5) , 158-165
- https://doi.org/10.1002/jlcr.1583
Abstract
No abstract availableKeywords
This publication has 11 references indexed in Scilit:
- The synthesis of tritiated (R)‐2‐methoxy‐N‐n‐propyl‐nor‐apomorphine (MNPA)Journal of Labelled Compounds and Radiopharmaceuticals, 2007
- Binding characteristics and sensitivity to endogenous dopamine of [11C]‐(+)‐PHNO, a new agonist radiotracer for imaging the high‐affinity state of D2 receptors in vivo using positron emission tomographyJournal of Neurochemistry, 2006
- Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: A comparison of the agonist radioligand [11C]MNPA and antagonist [11C]racloprideSynapse, 2006
- A preliminary PET evaluation of the new dopamine D2 receptor agonist [11C]MNPA in cynomolgus monkeyNuclear Medicine and Biology, 2005
- In vivo vulnerability to competition by endogenous dopamine: Comparison of the D2 receptor agonist radiotracer (–)‐N‐[11C]propyl‐norapomorphine ([11C]NPA) with the D2 receptor antagonist radiotracer [11C]‐racloprideSynapse, 2004
- Synthesis and dopamine receptor affinities of enantiomers of 2-substituted apomorphines and their N-n-propyl analogsJournal of Medicinal Chemistry, 1990
- 2-Haloaporphines as potent dopamine agonistsJournal of Medicinal Chemistry, 1989
- New methods and reagents in organic synthesis. 46. Trimethylsilyldiazomethane: A convenient reagent for the O-methylation of phenols and enols.CHEMICAL & PHARMACEUTICAL BULLETIN, 1984
- Aporphines. 34. (-)-2,10,11-Trihydroxy-N-n-propylnoraporphine, a novel dopaminergic aporphine alkaloid with anticonvulsant activityJournal of Medicinal Chemistry, 1981
- Preferential cleavage of an aromatic methylenedioxy group in the presence of methoxyls with boron trichlorideThe Journal of Organic Chemistry, 1972