IMMUNOCHEMICAL STUDIES ON INSULIN CONCERNING NEUTRALIZING ANTIBODIES
- 1 November 1958
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Biochemistry
- Vol. 45 (11) , 947-949
- https://doi.org/10.1093/oxfordjournals.jbchem.a126828
Abstract
The simultaneous injection of killed human-type tubercle bacilli (Aoyama B strain) and insulin as an emulsion to guinea pig produced 4 weeks later an antibody in blood serum, capable of suppressing the insulin convulsion effect in mice. This insulin-neutralizing factor was the protein which was precipitated by ammonium sulfate at half saturation and was non-dialyzable.This publication has 4 references indexed in Scilit:
- INSULIN-I131 METABOLISM IN HUMAN SUBJECTS: DEMONSTRATION OF INSULIN BINDING GLOBULIN IN THE CIRCULATION OF INSULIN TREATED SUBJECTS 1Journal of Clinical Investigation, 1956
- Antigenicity of insulin: diabetes induced by specific antibodiesBiochemical Journal, 1955
- IMMUNOLOGIC STUDIES IN INSULIN RESISTANCE. III. MEASUREMENT OF AN INSULIN ANTAGONIST IN THE SERUM OF AN INSULIN-RESISTANT PATIENT BY THE BLOOD SUGAR CURVE METHOD IN MICEJournal of Clinical Investigation, 1947
- IMMUNOLOGICAL IDENTITY OF INSULIN FROM VARIOUS SPECIES1Endocrinology, 1942