The Transfer of Glucose to Steroids by Chimpanzee Liver Microsomes

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Abstract
Microsomal preparations from chimpanzee liver can transfer glucose from UDPglucose to the 17α-hydroxyl group of 17α-estradiol and of 17α-estradiol-3-glucuronide. A phenolic glucoside of estrone, but not of either 17α- or 17β-estradiol is also formed. No formation of glucosides, of p-nitrophenol, or of diethylstilbestrol was demonstrated. The specificity of glucosyl transfer in the chimpanzee is not identical to that in either the human, the rabbit, or the sheep.

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