Solid-Phase Transimidation for the Removal of N-Phthalimido- and N-Tetrachlorophthalimido Protecting Groups on Carbohydrates
- 1 February 1996
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1996 (02) , 179-181
- https://doi.org/10.1055/s-1996-5356
Abstract
N-Phthalimido and N-tetrachlorophthalimido groups on carbohydrate derivatives are conveniently deprotected using alkyldiamines immobilized on polystyrene beads. The protecting group and reagent remain on the beads and the free amino sugar is recovered in 81-96% yield by simple filtration and evaporation.Keywords
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