Fibrosarcomas induced by cobalt chloride (CoCl2) in rats
Open Access
- 1 January 1977
- journal article
- research article
- Published by SAGE Publications in Laboratory Animals
- Vol. 11 (1) , 43-46
- https://doi.org/10.1258/002367777780959157
Abstract
Hyperlipaemia persisted for more than 12 months in rats treated with cobalt chloride. 9 of 20 treated rats and 1 control rat died within the first year, and 8 of the surviving animals developed fibrosarcomas-in 4 of these the tumour was far removed from the injection sites. The results are discussed with reference to the use of cobalt chloride treatment for anaemia in patients with chronic renal failure.Keywords
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