Utilization of Chloroagetone in the Synthesis of 3-Methylindoles
- 1 January 1992
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 22 (3) , 343-349
- https://doi.org/10.1080/00397919208055410
Abstract
Syntheses of 3-methylindoles 2 and 5 are described starting from chloroacetone and the corresponding monoalkylated anilines utilizing a modified alkylation-cyclization sequence. Compound 5 was converted in high yield into a very useful oxindole 7 in two steps.Keywords
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