Studies on peptide antibiotics, leucinostatins. I. Separation, physico-chemical properties and biological activities of leucinostatins A and B.

1 January 1983

journal article
research article
Published by Japan Antibiotics Research Association in The Journal of Antibiotics

Vol. 36 (12) , 1606-1612
https://doi.org/10.7164/antibiotics.36.1606

Abstract

Leucinostatin, a peptide antibiotic, was separated by silica gel and alumina column chromatography into 2 related components designated as leucinostatin A hydrochloride (C61H111N11O13.cntdot.HCl) and leucinostatin B hydrochloride (C61H109N11O13.cntdot.HCl). Physicochemical and biological properties [antifungal, antibacterial] of the 2 separated components were analyzed. These properties suggested similar chemical structures.

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