SOME SHORTCOMINGS OF DIRECT INTRAVENTRICULAR INJECTION IN MICE
Open Access
- 1 April 1974
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 50 (4) , 603-605
- https://doi.org/10.1111/j.1476-5381.1974.tb08596.x
Abstract
The use of X-ray photography following injection of iophendylate to verify that intraventricular injections in mice have been satisfactorily accomplished is misleading since it fails to detect leakage into the periphery. Radioactive labelling reveals that a substantial proportion of the injected material is rapidly carried to the periphery in the bloodstream.Keywords
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