Lymphokines
- 8 October 1987
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 317 (15) , 940-945
- https://doi.org/10.1056/nejm198710083171506
Abstract
LYMPHOKINES are polypeptide products of activated lymphocytes that participate in a variety of cellular responses, including the regulation of the immune system. They are released in response to antigen, but in contrast to the chemical composition of antibodies, their chemical composition is not determined by that of the stimulating antigen. Lymphokines were originally thought to be produced only by lymphocytes and to communicate with other cells of the immune system. It is now clear that neither the production of lymphokines nor their effects are restricted to lymphoid cells. For these reasons, the term "lymphokine" is yielding to the more general . . .Keywords
This publication has 38 references indexed in Scilit:
- The Basic Components of the Immune SystemNew England Journal of Medicine, 1987
- Acquired Defect in Interleukin-2 Production in Patients with Type I Diabetes MellitusNew England Journal of Medicine, 1986
- Regulation of B-lymphocyte activation, proliferation, and immunoglobulin secretionCellular Immunology, 1986
- Study of activated T cell in manClinical Immunology and Immunopathology, 1986
- Observations on the Systemic Administration of Autologous Lymphokine-Activated Killer Cells and Recombinant Interleukin-2 to Patients with Metastatic CancerNew England Journal of Medicine, 1985
- Expression and function of interleukin-2 receptors on immature thymocytesNature, 1985
- Interleukin-1 and the Pathogenesis of the Acute-Phase ResponseNew England Journal of Medicine, 1984
- Accessory cell function of human B cells. I. Production of both interleukin 1-like activity and an interleukin 1 inhibitory factor by an EBV-transformed human B cell line.The Journal of Experimental Medicine, 1984
- Alpha Interferon for Induction of Remission in Hairy-Cell LeukemiaNew England Journal of Medicine, 1984
- Regulation of B-Cell Growth and Differentiation by Soluble FactorsAnnual Review of Immunology, 1983