Evaluation of the Phadebact Gonococcus Test in the identification of Neisseria gonorrhoeae in a routine diagnostic laboratory.

Abstract
The Phadebact Gonococcus Test, a coagglutination procedure for the confirmation of identity of presumptive N. gonorrhoeae isolates, was evaluated under normal working conditions in a routine diagnostic laboratory and compared with an immunofluorescence technique. Of 166 isolates of N. gonorrhoeae from urogenital, rectal and pharyngeal sites (human), 164 gave a positive coagglutination reaction; 1 of the 2 negative isolates gave a positive reaction on retesting after subculture. There were no cross-reactions with other organisms tested. This was in contrast with the immunofluorescence technique; with this method, 3 of 46 isolates of N. meningitidis fluoresced brightly, and a further 17 isolates of N. meningitidis gave reactions that were difficult to interpret. The coagglutination test seemingly is rapid, simple and a more specific alternative to immunofluorescence.

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