Synthesis of 5′-alkylthio-5′-deoxynucleosides from nucleosides in a one-pot reaction
- 1 January 1983
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 7,p. 1315-1318
- https://doi.org/10.1039/p19830001315
Abstract
5′-Alkyl (aryl) thio-5′-deoxynucleosides [alkyl (aryl) nucleoside sulphides] were prepared in high yields by the reaction of nucleosides with dialkyl or diaryl disulphides in the presence of tri-n-butylphosphine. The method is widely applicable to the synthesis of unsymmetrical sulphides.This publication has 0 references indexed in Scilit: