EFFECT OF AGE AND DIET ON ELECTROLYTE CHANGES IN RAT MUSCLE DURING STIMULATION

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Abstract
The loss of K on stimulation of rat muscles is progressively greater as the duration of contractions is increased up to 30 mins. The changes in chloride and water are almost maximal after only 5 mins. of stimulation. The K loss and the chloride gain apparently bear a different relationship to the contraction process. It was found that immature rate lose more K from stimulated muscles than do adult rats. Feeding diets low in K and poisoning with monoiodacetic acid have little or no effect on the K changes during stimulation.

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