Pyrones. VIII. Biosynthetic investigations of the fungal metabolite phacidin
- 15 January 1982
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 60 (2) , 133-137
- https://doi.org/10.1139/v82-023
Abstract
Biosynthetic feeding experiments [using Poteboniamyces balsamicola] with singly and doubly 13C-labeled acetate show that phacidin (4-methoxy-6-nonanoyl-2H-pyran-2-one-3-carboxaldehyde) is formed from a heptaketide precursor. A similar feeding with sodium 13C-formate showed that the methoxyl and aldehyde carbons are derived from the 1-carbon pool.This publication has 3 references indexed in Scilit:
- Pyrones. VI. The total synthesis of phacidinCanadian Journal of Chemistry, 1980
- Use of 13C in biosynthetic studies. Incorporation of 13C-labeled acetate into chartreusin by StreptomyceschartreusisCanadian Journal of Chemistry, 1977
- In vitro growth inhibitory studies of phacidin against some dermatophytes, opportunistic and systemic fungi, and yeasts pathogenic on manJournal of Antimicrobial Chemotherapy, 1977