Management of the Common Cold

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Abstract
I. Primary Immunodeficiency 343II. Secondary Immunodeficiency Syndromes 344References 346I. Primary ImmunodeficiencyDespite technological advances in prenatal and early postnatal diagnosis forgenetically inherited immunodeficient diseases, most primary or congenitalimmunodeficiencies continue to be clinically detected because of recurrent, orunusually chronic infections. Among these, rhinosinusitis, which has been recog-nized as a source of infection in healthy children, plays a major role. Childrenwith cystic fibrosis, ciliary dyskinesia syndrome (which includes Kartagener’ssyndrome), and immunoglobulin deficiencies frequently present with radio-graphic evidence of chronic sinus disease (1,2).

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