Heterotransplantation of Human Fetal Pituitaries in Nude Mice*
- 1 August 1977
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 101 (2) , 365-368
- https://doi.org/10.1210/endo-101-2-365
Abstract
The heterotransplantation of minced human fetal pituitaries into adult thymus-aplastic nude mice is described. Development and growth of such grafts were observed in 16 of 21 recipient mice. Histological examinations of the transplants showed typical adenohypophyseal cells. Neurohypophyseal cells could never be detected. The levels of human growth hormone (hGH) varied between 0.8-42.0 ng/ml in the plasma of the hosts (mean value 7.2 ng/ml, by radioimmunoassay).This publication has 2 references indexed in Scilit:
- Absence of Thymus in a Mouse MutantNature, 1968
- The culture of mature organs in a synthetic mediumExperimental Cell Research, 1959