Cephalosporin derivatives with 2- and 4-pyridone groups at carbon-3

Abstract
Two compounds, analogs of cephalexin with 2- and 4-pyridone groups at C-3, were prepared. Biological evaluation found the compounds to exhibit activity against gram-positive and gram-negative organisms in vitro and in vivo [mouse]. The compounds were only active in vivo on s.c. administration.

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