Heterocyclic complexes of ruthenium(III) induce apoptosis in colorectal carcinoma cells
- 16 October 2004
- journal article
- research article
- Published by Springer Nature in Zeitschrift für Krebsforschung und Klinische Onkologie
- Vol. 131 (2) , 101-110
- https://doi.org/10.1007/s00432-004-0617-0
Abstract
The ruthenium complex salt indazolium trans-[tetrachlorobisindazole-ruthenate(III)] (KP1019) and the analogous sodium salt KP1339 are effective tumor-inhibiting drugs in experimental therapy of autochthonous colorectal carcinomas in rats. This paper examines the cell biological mechanisms underlying their antineoplastic effects.Keywords
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