Abstract
Fibrin film, a structural material derived from the proteins of human plasma involved in the natural coagulation process, has been implanted in rabbits and the absorption rate measured. Persistence times ranging from less than 5 days for untreated film to more than 80 days for fully treated film have been observed. Films of extended persistence time become encapsulated between 10 and 30 days after implantation. The choice of material for surgical use should be guided by the persistence time desired for each specific application.