Studies of mutagenicity on quiescent and proliferating hamster cell populations
- 1 March 1980
- journal article
- Published by Wiley in Cell Biology International Reports
- Vol. 4 (3) , 303-312
- https://doi.org/10.1016/0309-1651(80)90063-6
Abstract
A few known mutagens were tested on proliferating hamster cells and on cells made quiescent by L-histidinol block. No differences were found in the effectiveness of two alkylating agents and a base analogue; whereas the carcinogen 4-nitroquinoline-1-oxide was more effective on quiescent than on proliferating cells. The implications of these data on the mechanism of action of mutagens are discussed.Keywords
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