Pheochromocytoma as an Inherited Abnormality

Abstract
ALTHOUGH the first pathological description of pheochromocytoma, by Fränkel,1 appeared in 1886, it was not until 1922 that the association of pheochromocytoma and paroxysmal hypertension was described by Labbé et al.2 A cause- and-effect relation was established by Mayo3 in 1927, when he demonstrated that removal of such a tumor resulted in complete relief of the associated hypertension. Mayo's report stimulated widespread medical interest in pheochromocytoma as a potentially curable cause of hypertension. Although numerous publications have emphasized the diagnostic and therapeutic aspects of this condition, the familial occurrence of pheochromocytoma has received relatively little attention.The purpose of this . . .