Genetics of Fourteen Marker Systems: Associations and Linkage Relations

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Abstract
Fourteen genetic marker systems [ABO, MN, P, Rh, Lutheran, Kell, Duffy, Kidd, Hp, Gm, Gc, Lp, Se se and PTC] were examined in 155 Norwegian families with 570 children. This material, together with data of other workers, is considered with particular regard to linkage relations and associations. The most likely distribution of unmarked, singlemarked, doublemarked etc. chromosomes, given the applied number of marker systems, is considered, and the observations are interpreted against this background. A possible association between the Hp and Gm systems is noted, consisting essentially of an excess of double heterozygotes. No new case of linkage is established, although it appears likely that one or other of the higher test values represents a case of linkage.