GROWTH OF THE MALE GUINEA PIG MAMMARY GLAND WITH DIETHYLSTILBESTROL1,2
- 1 April 1942
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 30 (4) , 585-590
- https://doi.org/10.1210/endo-30-4-585
Abstract
Groups of 3 to 5 [male] guinea pigs were given subcut. injs. of diethylstilbestrol at dosages from 0.01 to 50.0 [mu]g. per day. Although no obvious signs of main duct growth were apparent some extension of the mammary glands appeared to have occurred at 0.1 [mu]g. per day and above. Lobule development occurred in all groups showing duct extension. Early lobules contained no alveoli but when developed further alveoli were numerous. Development of [male] mammary glands did not compare favorably with that secured in a single [female] treated. No secretion was observed in the [male] glands. The teats of [male] guinea pigs in all groups were larger than controls. Higher dosages caused no greater development than did 0.1 [mu]g. per day.This publication has 3 references indexed in Scilit:
- INHIBITION OF MAMMARY GROWTH BY LARGE AMOUNTS OF ESTROGEN1Endocrinology, 1941
- Über die Wirkung von weiblichen Sexualhormonen auf die MeerschweinchenzitzeHelvetica Chimica Acta, 1940
- Studies on the physiology of lactation. VI. The endocrine influences con cerned in the development and function of the mammary gland in the guinea pigJournal of Anatomy, 1937