Correlation of Myocardial Ultrastructure and Function
Open Access
- 1 July 1968
- journal article
- review article
- Published by Wolters Kluwer Health in Circulation
- Vol. 38 (1) , 29-44
- https://doi.org/10.1161/01.cir.38.1.29
Abstract
The electron microscopic structure of heart muscle and the ultrastructural basis of cardiac contraction have been reviewed. The relation between muscle length and developed tension has been explained in terms of the structure of the sarcomere, which is the basic unit of contraction. Using the derived length-tension curve of the sarcomere, developed tension has been attributed to the overlap of thick and thin filaments within the sarcomere, lending support to the "sliding" mechanism in heart muscle.Keywords
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