ENZYME LINKED IMMUNOSORBENT ASSAY IN DIAGNOSIS OF HUMAN BILHARZIASIS

  • 1 January 1978
    • journal article
    • research article
    • Vol. 29  (1) , 12-14
Abstract
Sera from 72 persons with ova of Schistosoma mansoni and/or S. haematobium in stools or urine, 16 persons from schistosomiasis-endemic areas but without demonstration of ova and 9 healthy persons from areas with no schistosomiasis (control) were examined with ELISA [enzymic linked immunosorbent assay] using antigen from adult S. mansoni worms. All parasitologically proven cases had extinction values higher than those of controls. False positive results were obtained in 11 of 16 persons from endemic areas but without ova, probably due to cross-reactions, a past history of schistosomiasis or a missed diagnosis of S. mansoni infections. Cases with S. haematobium and those with S. mansoni showed significantly different extinction values. Differences between the sexes were not statistically significant.