Lymphomatoid Granulomatosis Manifested as a Mass in the Cerebellopontine Angle

Publisher Website
Google Scholar
Abstract
Lymphomatoid granulomatosis, first described by Liebow et al1 in 1972, is a rare clinical entity characterized by angiocentric, angiodestructive lymphoreticular proliferation and granulomatous reaction. It initially involves primarily the lung, and in a subsequent sarcomatous stage extrapulmonary tissues are involved. We have recently encountered a case of lymphomatoid granulomatosis with nodular pulmonary infiltrates and symptoms of a rapidly growing mass in the cerebellopontine angle. Central nervous system involvement is by no means uncommon, as it occurs in at least 20% of all patients with lymphomatoid granulomatosis.1-3 In patients with rapidly developing CNS symptoms associated with nodular lung lesions, lymphomatoid granulomatosis should be considered a strong candidate in the differential diagnosis. REPORT OF A CASE In a 54-year-old man, malaise, restlessness, intermittent fever, and a 15-kg weight loss occurred during the year before admission. Initially, he was treated for a bacterial pneumonia because of bilateral nodular infiltrates shown on

This publication has 2 references indexed in Scilit: