Allopurinol Sensitivity in a Patient With Chronic Tophaceous Gout: Success of Intravenous Desensitization After Failure of Oral Desensitization
- 10 October 1991
- journal article
- case report
- Published by Wiley in Arthritis & Rheumatism
- Vol. 34 (10) , 1329-1331
- https://doi.org/10.1002/art.1780341020
Abstract
Sensitivity to allopurinol, which occurs in 10–15% of patients, can seriously limit the drug's use in chronic tophaceous gout. Oral allopurinol desensitization has been advocated for sensitive patients in whom use of the drug is warranted. We report the successful use of intravenous allopurinol desensitization in a patient with chronic tophaceous gout in whom oral desensitization had previously failed.Keywords
This publication has 11 references indexed in Scilit:
- Desensitisation to allopurinol.Annals of the Rheumatic Diseases, 1987
- Desensitisation to allopurinol: a cautionary tale.Annals of the Rheumatic Diseases, 1987
- Desensitisation to allopurinol.Annals of the Rheumatic Diseases, 1987
- Sulphasalazine in rheumatoid arthritis: desensitising the patient with a skin rash.Annals of the Rheumatic Diseases, 1986
- The allopurinol hypersensitivity syndrome. Unnecessary morbidity and mortalityArthritis & Rheumatism, 1986
- Allopurinol hypersensitivity in a patient with severe, chronic, tophaceous goutArthritis & Rheumatism, 1985
- Severe allopurinol toxicityThe American Journal of Medicine, 1984
- Desensitization of patients allergic to penicillin using orally administered β-lactam antibiotics*Journal of Allergy and Clinical Immunology, 1982
- Controlled Penicillin Anaphylaxis Leading to DesensitizationSouthern Medical Journal, 1974
- SPECIFIC HYPOSENSITIZATION OF PATIENTS WITH PENICILLIN ALLERGYAllergy, 1969