Unilateral Vesicoureteral Reflux in Children

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Abstract
Vesicoureteral reflux was defined as unilateral in 17 of 36 cases. Urine was collected from both kidneys. Urine specific gravity and osmolality were significantly reduced; β(2)-microglobulin was elevated and lactoferrin depressed on the reflux side. We also observed a significant correlation between specific gravity or osmolality on one side and lactoferrin on the other side, and between osmolality and β(2)-microglobulin. These observations showed a depressed concentrating capacity and reduced tubular absorption of β(2)-microglobulin suggesting reduced tubular function on the reflux side.

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