Repeat radiation synovectomy with dysprosium 165—ferric hydroxide macroaggregates in rheumatoid knees unresponsive to initial injection

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Abstract
Because of failure to fully respond to an initial intraarticular injection of dysprosium 165–ferric hydroxide macroaggregates, 17 patients with seropositive rheumatoid arthritis underwent repeat radiation synovectomy using this agent. Of the 13 patients who were evaluated 1 year later, 54% (7 knees) had good results, 31% (4 knees) had fair results, and 15% (2 knees) had poor results. The initial lack of significant benefit from radiation synovectomy did not appear to preclude a favorable response to a second injection.