Quantitative morphology of the corpus callosum in attention deficit hyperactivity disorder
- 1 May 1994
- journal article
- Published by American Psychiatric Association Publishing in American Journal of Psychiatry
- Vol. 151 (5) , 665-669
- https://doi.org/10.1176/ajp.151.5.665
Abstract
By means of quantitative neuroanatomic imaging the authors assessed the hypothesis that there are structural brain abnormalities relevant to frontal lobe circuitry in children with attention deficit hyperactivity disorder (ADHD). The midsagittal cross-sectional area of the corpus callosum, divided into seven sections, was measured from magnetic resonance images of 18 boys with ADHD and 18 carefully matched normal boys. Two anterior regions, the rostrum and the rostral body, were found to have significantly smaller areas in the ADHD group. These areas correlated in the expected direction with teacher and parent ratings of hyperactivity/impulsivity. This finding supports theories of abnormal frontal lobe development and function in ADHD.Keywords
This publication has 13 references indexed in Scilit:
- The Functional Neuroanatomy of Psychiatric TreatmentsPsychiatric Clinics of North America, 1991
- Integrated phylogeny of the primate brain, with special reference to humans and their diseasesBrain Research Reviews, 1990
- LATE CHILDHOOD CHANGES IN BRAIN MORPHOLOGY OBSERVABLE WITH MRIDevelopmental Medicine and Child Neurology, 1990
- Striatal Dysfunction in Attention Deficit and Hyperkinetic DisorderArchives of Neurology, 1989
- Reliability, validity, and Parent-Child Agreement Studies of the Diagnostic Interview for Children and Adolescents (DICA)Journal of the American Academy of Child & Adolescent Psychiatry, 1987
- Focal Cerebral Hypoperfusion in Children With Dysphasia and/or Attention Deficit DisorderArchives of Neurology, 1984
- DEFICITS IN ATTENTION AND MOVEMENT FOLLOWING THE REMOVAL OF POSTARCUATE (AREA 6) AND PREARCUATE (AREA 8) CORTEX IN MACAQUE MONKEYSBrain, 1983
- Normative data on Revised Conners Parent and Teacher Rating ScalesJournal of Abnormal Child Psychology, 1978
- Patterns of the somesthetic messages transferred through the corpus callosumExperimental Brain Research, 1974
- Hyperkinetic Impulse Disorder in Childrenʼs Behavior ProblemsPsychosomatic Medicine, 1957