Effect of Ampicillin Therapy on Urinary Amino Acid Patterns

Publisher Website
Google Scholar
Abstract
To the Editor: Recently, we were involved in the investigation of a child with massive liver enlargement who later died of a hepatoblastoma. The child's urinary amino acid pattern was not strikingly unusual, but it did show a compound in the area of cystathionine or cystine. Normally, sulfur-containing amino acids can be identified by oxidization of the urine with hydrogen peroxide; cystine then becomes cysteic acid and cystathionine becomes cystathionine sulfoxide etc. When the urine specimen from this child was treated with hydrogen peroxide and rechromatographed, the cystathionine spot moved to the area of cystathionine sulfoxide, but the striking finding . . .

This publication has 0 references indexed in Scilit: