PURPURA HAEMORRHAGICA FOLLOWING THE ADMINISTRATION OF NEOARSPHENAMINE
- 1 September 1936
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1908)
- Vol. 58 (3) , 495-511
- https://doi.org/10.1001/archinte.1936.00170130124007
Abstract
Hemorrhage following the therapeutic use of the arsphenamines apparently was not reported until 1916, when Evans1mentioned the occurrence but did not connect it definitely with arsphenamine. Three years later (1919) two French observers, Labbé and Langlois,2called attention to the fact that purpuric manifestations are a complication of the arsphenamine therapy of syphilis. McCarthy and Wilson3in 1932 reviewed the published reports of eleven cases of purpura haemorrhagica following the use of arsphenamine and reported two of their own cases. Loveman4in 1932 was able to find reports of fourteen instances of purpura haemorrhagica following arsphenamine treatment up to 1931, when his article was sent to the publishers. With one new case included in his report, the total number of cases reported up to 1932, on the basis of Loveman's statistics, was seventeen (including the two cases reported by McCarthy and Wilson). Since 1932 thereThis publication has 0 references indexed in Scilit: