Chronic allograft nephropathy—a model of impaired repair from injury?
Open Access
- 1 February 2000
- journal article
- review article
- Published by Oxford University Press (OUP) in Nephrology Dialysis Transplantation
- Vol. 15 (2) , 149-151
- https://doi.org/10.1093/ndt/15.2.149
Abstract
Chronic allograft nephropathy (CAN) is characterized by excessive tissue fibrosis and sclerosis, resulting in the disruption of the tissue architecture (Figure 1). The common thread of transplants with CAN is that they all have undergone previous tissue injury, and recent experimental data suggest that the excessive fibrosis results from impaired repair from injury.Keywords
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