Cerebral changes related to duration of environmental complexity and locomotor activity.

Abstract
Experiment 1 compared effects of varying durations (14, 7, and 3 days) of environmental complexity (ECT) on brain weight and on total and specific activity of brain acetylcholinesterase (AChE) in 48 littermate pairs of rats. Significant increase for ECT Ss in weight of sensory cortex, total cortex, and cortical/subcortical (C/S) ration were found; no effect on total activity of AChE were observed; significant decreases in specific activity of AChE occurred in the sensory cortex and in the C/S ratio for ECT Ss. Experiment 2 compared the effects of locomotor activity (14 days) on the cerebral measures. No significant brain differences were found between litter-mates; correlations of wheel revolutions with cerebral measures were low and inconsistent.

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