Targets for the Antiviral and Antitumor Activities of Nucleoside, Nucleotide and Oligonucleotide Analogues
- 1 February 1985
- journal article
- plenary lectures
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 4 (1-2) , 3-11
- https://doi.org/10.1080/07328318508077826
Abstract
The following targets can be considered in the development of antiviral agents: (i) DNA polymerase via dThd kinase, (ii) S-adenosylhomocysteine hydrolase; and in the development of antitumor agents: (iii) dTMP synthetase and (iv) protein synthesis via the 2–5A pathway.Keywords
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