A gene that encodes a protein consisting solely of zinc finger domains is preferentially expressed in transformed mouse cells.
Open Access
- 1 January 1990
- journal article
- research article
- Published by Taylor & Francis in Molecular and Cellular Biology
- Vol. 10 (1) , 418-421
- https://doi.org/10.1128/mcb.10.1.418
Abstract
We describe the cloning and characterization of the mouse MOK-2 gene, a new member of the Krüppel family of zinc finger proteins. Sequencing of both cDNA and genomic clones showed that the predicted MOK-2 protein consists of seven zinc finger domains with only five additional amino acids. The finger domains of MOK-2 are highly homologous to one another but not to those of other zinc finger proteins. MOK-2 is preferentially expressed in transformed cell lines, brain tissue, and testis tissue. Its possible role in cellular transformation is discussed.This publication has 36 references indexed in Scilit:
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