Evidence that Ferrihemoglobin May Function as an Intracellular Heme Carrier in Reticulocytes
- 1 August 1974
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Biochemistry
- Vol. 52 (8) , 665-669
- https://doi.org/10.1139/o74-095
Abstract
Ferrihemoglobin can (1) stimulate globin synthesis in rabbit reticulocytes and in a reticulocyte cell-free protein synthesizing system, and (2) cause newly synthesized αβ-globin dimers to form tetramers which are indistinguishable from hemoglobin in the ultracentrifuge.These observations are consistent with the idea that a small pool of ferrihemoglobin may act as an intracellular heme carrier in reticulocytes.Keywords
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