Synthesis of 4-L-Leucine-6-O-acetyl-L-serine, 4-L-Leucine, 6-O-Acetyl-L-serine Bradykinin, and Bradykinin

Abstract
An alternate synthesis of bradykinin and the synthesis of three analogs of bradykinin is described, in which 4 glycine has been substituted with L-leucine and 6 L-serine has been substituted with O-acetyl-L-serine. The biological activity of 3 analogs were compared with that of bradykinin.