Detection of the lipid‐linked precursor oligosaccharide of N‐linked protein glycosylation in Drosophila melanogaster
- 23 September 1991
- journal article
- Published by Wiley in FEBS Letters
- Vol. 290 (1-2) , 58-60
- https://doi.org/10.1016/0014-5793(91)81225-w
Abstract
The presence of a glycan of the same molecular size as the lipid linked precursor oligosaccharide (Glc3Man9GlcNAc2) of the N-linked protein glycosylation pathway in mammalian cells has been detected in a glycolipid fraction of cultured Drosophila melanogaster cells. Oligosaccharide sequencing studies were consistent with the existence of a glucosylated high mannose containing structure, which may be the common precursor for N-linked protein glycosylation in insect cells.Keywords
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