PENICILLIN IN DERMATOLOGY
- 1 July 1946
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology and Syphilology
- Vol. 54 (1) , 19-24
- https://doi.org/10.1001/archderm.1946.01510360023002
Abstract
THE remarkable antibacterial properties and the relatively low toxicity of penicillin make it a logical agent to use against cutaneous pyogenic infections. Penicillin, in local applications, was first used by Fleming as early as 1929.1 Florey and Florey2 stated: "In essence, the problem of using penicillin locally is that of devising some means to apply a very soluble and diffusible substance, so that a bacteriostatic concentration is constantly maintained at every point where there are infecting organisms." The local use of penicillin in the treatment of burns and scaldings was satisfactory with a freshly prepared cream of penicillin.3 One of the earliest reports on the use of penicillin in dermatology was made by Roxburgh, Christie and Roxburgh.4 They reported satisfactory results in cases of sycosis barbae, impetigo, blepharitis and also some cases of eczema with secondary infection. Sophian and Connolly5 foundKeywords
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