Evidence Against Insulin Synthesis BY IM-9 Lymphocytes
- 1 February 1982
- journal article
- Published by American Diabetes Association in Diabetes
- Vol. 31 (2) , 182-184
- https://doi.org/10.2337/diab.31.2.182
Abstract
Insulin concentrated from acid/ethanol extracts of IMg lymphocytes by the use of octadecylsilyl (ODS) silica cartridges averaged 0.13 ng/ml cell volume compared with the 0.12 ng insulin/ml cell culture medium. The insulin content of these cells appears to be < 1% of previously reported values and probably could be accounted for by concentration of insulin from the incubation medium on cell receptors.Keywords
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