Involvement of annexin V in the entry of influenza viruses and role of phospholipids in infection

Abstract
Influenza viruses bind to annexin V, a widely spread non‐glycosylated phospholipid‐binding protein. Externally added phospholipids as well as antiserum against this protein specifically inhibit infection of these viruses in cell cultures. We conclude that annexin V plays an important role in the entry of these viruses.