3-Phosphoglyceric Acid Dehydrogenase from the Silk Gland

Abstract
The homo-genates of posterior silkglands of Bombyx mori with 0.1 M barbital buffer (pH 8.0), containing 0.001 M MgCl2, were centrifuged, and the supernatant was fractionated by ammonium sulfate between 0.55 and 0.65 saturation. The preparation stoichiometrically oxidized 3-phosphoglyceric acid to 3-phosphohydroxypyruvic acid at pH 10 by the presence of reduced glutathione, MgCl2, and diphosphopyridine nucleotide, which could not be replaced by trfphosphopyridine nucleotide.

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