ACAT inhibitors: evolution from cholesterol-absorption inhibitors to antiatherosclerotic agents
- 31 January 1998
- journal article
- review article
- Published by Elsevier in Drug Discovery Today
- Vol. 3 (1) , 19-25
- https://doi.org/10.1016/s1359-6446(97)01123-9
Abstract
No abstract availableThis publication has 36 references indexed in Scilit:
- Difference between Normal and WHHL Rabbits in Susceptibility to the Adrenal Toxicity of an Acyl-CoA:Cholesterol Acyltransferase Inhibitor, FR145237Toxicology and Applied Pharmacology, 1996
- Effect of FR145237, a novel ACAT inhibitor, on atherogenesis in cholesterol-fed and WHHL rabbits. Evidence for a direct effect on the arterial wallBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1995
- Hepatic and Adrenal Toxicity of a Novel Lipid Regulator in Beagle DogsFundamental and Applied Toxicology, 1995
- The structure of acyl coenzyme A-cholesterol acyltransferase and its potential relevance to atherosclerosisTrends in Cardiovascular Medicine, 1994
- RP 73163, a novel systemic ACAT-Inhibitor induces coarse vacuolation and impairs steroid hormone metabolism in guinea pig adrenocortical cellsToxicology Letters, 1994
- Subacute Toxicity of a Novel Inhibitor of Acyl-CoA: Cholesterol Acyltransferase in Beagle DogsFundamental and Applied Toxicology, 1993
- ATP Depletion Is Associated with Cytotoxicity of a Novel Lipid Regulator in Guinea Pig Adrenocortical CellsToxicology and Applied Pharmacology, 1993
- Atherosclerotic risk factors — are there ten, or is there only one?Atherosclerosis, 1992
- Clinical Implications of New Drugs for Lowering Plasma Cholesterol ConcentrationsDrugs, 1991
- Metabolism of cholesteryl ester in monolayers of bovine adrenal cortical cells. Effect of an inhibitor of acyl-CoA : cholesterol acyltransferaseBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1985