Lower Genital Tract Infections in Women: Comparison of Clinical and Epidemiologic Findings with Microbiology

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Abstract
We screened 392 women attending the Laboratory of Microbiology of Toulouse Purpan Hospital for symptoms of lower genital tract infection for six microorganisms. Rates of isolation of Neisseria gonorrhoeae, Chlamydia trachomatis, Candida albicans, Mycoplasma hominis, and Gardnerella vaginalis were 1%, 7.7%, 29.8%, 23.8%, and 37.5%, respectively. Trichomonas vaginalis was detected by direct examination in specimens from 3.1% of patients. Another goal of this study was to determine the relative prevalence of these microorganisms in relation to clinical and epidemiologic findings. C. trachomatis was isolated significantly more often from patients under 25 years old (P < 0.001), from those who use oral contraceptives (P < 0.01), from those who have a male sexual partner with symptoms of sexually transmitted disease (P < 0.001), and from those who present signs of cervicitis (P < 0.05). Isolation of C. albicans was significantly associated with vulvar pruritis (P < 0.01), vulvitis (P < 0.01), and vaginitis (P < 0.001). G. vaginalis and M. hominis are significantly associated with bacterial vaginosis (P < 0.001). This syndrome was diagnosed clinically in 27.2% of our study population and was highly correlated with use of an intrauterine device (P < 0.05).
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